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Mechanobiology Symposium 2026

MAY 27 – 29, 2026
Weill Hall
Cornell University, Ithaca, NY


Schedule
Wednesday | Thursday | Friday
Parking Information


About

The Mechanobiology Hub Summer Symposium will bring together faculty, postdoctoral researchers, graduate students, and other trainees from Cornell University and neighboring institutions to strengthen and expand our regional mechanobiology community. Rooted in the Hub’s mission, the symposium is designed to connect researchers across disciplines, scales, and systems who share an interest in how mechanical forces shape biology and disease.

The symposium will provide an opportunity to learn about ongoing mechanobiology research spanning cell and molecular biophysics to tissue and organ mechanics, with applications in development, cardiovascular and musculoskeletal biology, cancer, and beyond, highlight shared technologies and expertise, and spark new collaborations and initiatives.

Above all, this meeting aims to build community: to create space for conversation, discovery, and the exchange of ideas among established investigators, early-career researchers, and trainees. By bringing together diverse perspectives in a collegial setting, we hope to identify new opportunities to strengthen the local mechanobiology community, increase its visibility, and to foster the cross-disciplinary partnerships needed to accelerate discovery and innovation in mechanobiology.


KEYNOTE SPEAKER 

Dr. Amy E. Shyer, Ph.D., Associate Professor, The Rockefeller University

“Reciprocally constituting cell–supracellular structures as the generative force of tissue self-organization

Dr. Shyer heads the Laboratory of Morphogenesis and studies the mechanical forces and molecular cues that guide tissue formation in the developing embryo.



1:00 p.m.Welcome and Opening Remarks – 226 Weill Hall
1:15 p.m.Scientific Talks – 226 Weill Hall

Moderator: Gening Dong

Kayla Wolf (Cornell University)
Elucidating drivers of uterine contractility in engineered tissues

Chen Cheng (Binghamton University)
Low Wall Shear Stress Promotes Atheroma via Arterial Iron Accumulation

Julien Morival (Cornell University)
Investigating Nuclear Mechanotransduction by Mapping Genome-wide Changes
in Transcription and Chromatin Accessibility in Response to Mechanical Stretch

Karl Lewis (Cornell University)
A novel intravital imaging approach for studying the role of membrane dynamics
in bone cell mechanotransduction in mice in vivo

Jedidiah Tulu (Syracuse University)
Elasticotaxis in Myxococcus xanthus: A Unified Response to Substrate
Compression
2:30 p.m.Coffee Break
3:00 p.m.Keynote talk – 226 Weill Hall

Amy Shyer (Rockefeller University)
Reciprocally constituting cell–supracellular structures as the generative
force of tissue self-organization
4:00 p.m.Poster Flash Talks – 226 Weill Hall
4:45 p.m. Poster Session & Refreshments – 226 Weill Hall
6:30 p.m.Dinner – Weill Hall, 2nd Floor Atrium
9:30 a.m.Scientific Talks – 226 Weill Hall

Moderator: Si Chen

John Zimmerman (Cornell University)
Tissue Engineered Microphysiological Systems As Models of
Heart Disease

Mrinal Pandey (Cornell University)
3D mechanical compression suppresses STAT1/IFN signaling
in breast tumor spheroids

Duy Nguyen (Moffitt Cancer Center)
Physical and metabolic regulators of cancer cell dormancy

Brianna Knode (Cornell University)
Adipose-mimetic granular hydrogels reveal biophysical cues
driving breast cancer invasion

Changhao Li (Penn State University)
Collective microfibril sliding underlies plant cell wall creep
10:45 a.m.Coffee Break
11:15 a.m.Scientific Talks – 226 Weill Hall

Moderator: Chia-Jen Chang

Michelle Wang (Cornell University)
Genome Mechanics: Tension and Torsion
during Transcription and Replication

Gabrielle Inserra (University at Buffalo)
Mechanotherapeutic Potential of Survivin in Glioblastoma

Rachel Chen (Cornell University)
Multiphysics Modeling of Heterogeneous Biofilm Mechanics Across
Spatiotemporal Evolution

Nuzhat Faiza Nufa (Syracuse University)
Vimentin Regulates Collective Migration and Invasion Under Compressive
Stress in 3D-Spheroids
12:15 p.m. Lunch with working group discussions – Weill Hall, various rooms
View topics
1:45 p.m. Reporting from working groups – 226 Weill Hall
2:45 p.m. Scientific Talks – 226 Weill Hall

Moderator: Anna Hazelwood

Esak Lee (Cornell University)
Tumor lymphatic contractility drives drainage
failure and immune exclusion

Moumita Das (Rochester Institute of Technology)
Rigidity and Resilience of biopolymer networks in cells and tissues

Mia Huang (Cornell University)
Differential effects of continuous and intermittent salt-inducible
kinase inhibition on cortical and cancellous
bone responses to mechanical loading
3:30 p.m. Coffee Break
3:45 p.m.Scientific Talks – 226 Weill Hall

Moderator: Mingming Wu

Negin Majedin (Cornell University)
Can the Mechanics of Materials Reawaken Antitumor Immunity?

Andrew Lombardo (University at Buffalo)
Visualization of Myosin-9b processivity in Human cells
4:15 p.m.Science Speed Dating – 226 Weill Hall
5:00 p.m.Activity

9:00 a.m.Business meeting
o   Future meetings (frequency, sponsorship, conference grants)
o   Branding and visibility of mechanobiology
o   Training grants, center grants
9:45 a.m. Scientific Talks – 226 Weill Hall

Moderator: Adrienne Roeder

Nelly Andarawis-Puri (Cornell University)
The State Decides: Why Tendons Heal or Degenerate

Gening Dong (Cornell University)
Organotypic slice culture reveals tissue morphodynamics during ventricular
myocardial development

Aiyana Fortin (Cornell University)
Collagen-derived macropeptides rapidly penetrate articular cartilage and
associate with extracellular collagen
10:30 a.m. Coffee Break
11:00 a.m. Scientific Talks – 226 Weill Hall

Moderator: Larry Bonassar

Eric Dufresne (Cornell University)
Potential roles for biomolecular condensates in mechanobiology

Lanxi Hu (Cornell University)
Variability Generates Possibilities: Fluctuating Cell Growth Generates Robustness
to Flower Morphogenesis Under External Perturbation

Colm Kelleher (Syracuse University)
Active Liquid Crystal Physics Governs the Collective Behavior of the Spindle
Microtubule Network.
11:45 a.m. Closing Remarks

Topics for Working Groups

  1. Suggestions for future activities for the Mechanobiology Hub.
  2. How to create more regional interactions/connections/collaborations and raise the profile of the Mechanobiology Hub and regional mechanobiology across campus and at the national level.
  3. How to encourage interactions between theorists/modelers and experimentalists, using AI in mechanobiology.
  4. How to encourage cross-kingdom interactions (e.g., between plant science, single cell, animals…).
  5. Education, training, career and professional development (inside and outside academia).
  6. How can mechanobiology have an impact in the real world? Fostering connections with industry, clinicians, and other application areas.
  7. New ideas for tool development.
  8. Outreach to the general public.

Limited parking is available near the Weill Hall (237 Tower Road, Ithaca, NY 14853) via ParkMobile. Please look for green ParkMobile signs and pay using the ParkMobile app or phone number posted on-site (zone numbers vary by lot).

See Cornell Parking Services for details on using ParkMobile to park on campus and view this map for parking options.

[Zone 4131, Crescent Lot, will likely have the most availability and is just a short walk to Weill Hall]

Organizing Committee (Faculty)

  • Larry Bonassar: Daljit S. and Elaine Sarkaria Professor, Biomedical Engineering & Professor, Mechanical and Aerospace Engineering
  • Jan Lammerding: Professor & Associate Director, Biomedical Engineering
  • Adrienne Roeder: Professor, School of Integrative Plant Science, Plant Biology Section
  • Mingming Wu: Professor, Biological and Environmental Engineering

Organizing Committee (Students & Postdocs)

  • Chia-Jen Chang: Graduate Student, Fischbach Lab, Biomedical Engineering
  • Si Chen: Postdoctoral Associate, Roeder Lab, Weill Institute for Cell and Molecular Biology
  • Gening Dong: Graduate Student, Butcher Lab, Biomedical Engineering
  • Anna Hazelwood: Graduate Student, Lammerding Lab, Biomedical Engineering

Administrative Support

  • Jeff Ceria: Administrative Assistant, Faculty Support, Weill Institute for Cell and Molecular Biology
  • Stephen D’Angelo: Manager of Research Communications, Biological Systems, Research & Innovation